Investors seeking the best cryptocurrencies to buy this weekend should consider Qubetics, Bitcoin, Ethereum, Binance Coin, and Cardano. Qubetics, the first Web3 aggregator, is generating excitement with its upcoming mainnet launch, potentially boosting its token price significantly. Bitcoin remains a reliable asset, while Ethereum leads in smart contracts, Binance Coin offers strong utility, and Cardano stands out for its eco-friendly approach and research-driven development.